113 Psychoactive Meds

SSRI:

Drug Trade Name mg dosage
Citalopram (Celexa) 20-80
Fluoxetine (Prozac) 20-80
Paroxetine (Paxil) 20-80
Sertraline (Zoloft) 50-300
  • Fewest drug/drug interactions: citalopram, sertraline
  • Sedation, discontinuation syndromes: paroxetine

SNRI:

Drug Trade Name mg dosage
Venlafaxine (Effexor) 37.5-300
Duloxetine (Cymbalta) 20-120
  • for neuropathic pain at least 60 mg qd

Atypical:

Drug Trade Name mg dosage Notes
Bupropion (Wellbutrin) 100-450 seizure risk
Mirtazapine (Remeron) 15-45 increased appetite, weight gain

2nd generation Anti-Psychotic Agents:

Drug Trade Name mg dosage
Haloperidol (Haldol) 2.5-15
Risperidone (Risperdal) 1-6
Olanzapine (Zyprexa) 2.5-30
Aripiprazole (Abilify) 5-30
Quetiapine (Seroquel) 25-800
Clozapine (Clozaril) 250-450

Benzodiazepines:

Drug Trade Name mg dosage equivalent PO dose mg
Alprazolam (Xanax) 0.25-3 0.5
Clonazepam (Klonopin) 0.25-3 0.25
Diazepam (Valium) 2.5-20 5.0
Lorazepam (Ativan) 0.5-5 1.0
Flurazepam (Dalmane) 15-30 30
Temazepam (Restoril) 10-20 20

GABAa – Sleep Agents:

Drug Trade Name mg dosage
Zaleplon (Sonata) 5-10
Zolpidem (Ambien) 5-10

Other:

Drug Trade Name mg dosage
Buspirone (Buspar) 10-45
Trazodone 25-100

 

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Reference Notes for Palliative Care Consultation Copyright © 2018 by Robert F. Johnson MD, MEd is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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