108 PCN Methadone Notes 2
- This table incorporates:
- Incomplete cross tolerance
- Variations in metabolism
- Imperfections in equianalgesic tables
- Do not decrease after conversion
| OME mg/24 hrs | Morphine to Methadone Ratio |
| Less than 100 | 3:1 |
| 101-300 | 5:1 |
| 301-600 | 10:1 |
| 601-800 | 12:1 |
| 801-1000 | 15:1 |
| Greater than 1000 | 20:1 |
Oral methadone to IV methadone = 2:1
