110 PCN Fentanyl Notes 2

  • 50 mcg/hr Fentanyl TD = OME 100
  • IV Fentanyl
    • Peak effect IV push = 6-10 minutes
    • Duration of effect = 30-90 minutes
  • Conversion to IV Fentanyl:
    • 100 mcg IV Fentanyl = 10 mg IV Morphine
      • (for bolus dosing or do not decrease for cross tolerance)
    • 100 mcg Fentanyl IV = 6.6 mg Morphine Sulfate
      • (for continuous infusion)
  • TransDermal to IV Fentanyl – decrease by 50%
  • IV to TD – 1:1

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Reference Notes for Palliative Care Consultation Copyright © 2018 by Robert F. Johnson MD, MEd is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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