121 Correlation of Mechanisms/Receptors with Medications

  • CTZ, opiods > D2 >
    • metoclopramide, prochlorperazine, chlorpromethazine, haloperidol, olanzapine
  • ChemoRx, RT, opioids, uremia, post-op > 5-HT3>
    • ondansetron, dexamethasone
  • Bowel obstruction > D2, Ach >
    • metoclopramide, haloperidol/olanzapine, dexamethasone, hyoscyamine
  • Motion > H1 >
    • scopolamine, diphenhydramine, promethazine

Sample Agents:

Metoclopramide D2 (GI), 5HT2
Prochlorperazine D2 (CTZ)
Chlorpromazine D2 (CTZ)
Promethazine D2, H1, Ach
Diphenhydramine H1
Scopolamine H1
Hyoscyamine Ach
Ondansetron 5HT3
Mirtazapine 5HT3
Olanzapine D2, Ach, H1, 5HT3
Haloperidol D2
Propofol 5HT3

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Reference Notes for Palliative Care Consultation Copyright © 2018 by Robert F. Johnson MD, MEd is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, except where otherwise noted.

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