109 PCN Fentanyl (F) Notes

• For bolus dosing: 100 mcg (0.1 mg) F = 10 mg Morphine IV = 30 mg Morphine PO
• For continuous infusion: 100 mcg (0.1 mg) F/hr = 6.6 mg Morphine/hr
• F TTD to F IV: decrease by 50%
• F IV to F TTD: 1:1
• OME to F TTD: OME/2

F IV peak effect 6-10 min, duration 30-90 min

• F TTD doses available: mcg/hr 12, 25, 50, 75, 100
• F oral lozenge (Actiq) = OTFC 200 mcg OTFC =
  • 12 mg Morphine PO
  • 2-4 mg Morphine IV
  • 7.5 mg oxycodone PO
• OTFC mcg doses sizes available: 200, 400, 600, 800, 1200, 1600
• F buccal tablets (Fentora): 2X strength of OTFC
  • dose sizes available: 100, 200, 400, 600, 800