2 Cardiac Related Conditions Commonly Seen in Cardiac Rehab

Before getting into the details about heart rhythms, medical interventions, and exercise prescription, it might be a good idea to do a quick overview of common cardiac conditions that the clinical exercise physiologist will be working with. This chapter is only meant to briefly introduce the conditions, and not to discuss pathophysiology. More will be discussed in later chapters.

 

Atherosclerosis: it’s everywhere!

Vascular disease begins the day we are born. Progressive damage, inflammation, and cholesterol plaque accumulation in blood vessels throughout the body are present in everyone. However, the rate of progression will vary, based on lifestyle and risk factors, such as:

  • Sedentary lifestyle
  • High Blood pressure
  • Dyslipidemia (high LDL, low HDL cholesterol)
  • Tobacco use
  • Diabetes
  • Obesity

Given the high proportion of individuals that are overweight, inactive, and metabolically unstable, it is no wonder that cardiac disease is the leading killer of men and women.

Vascular disease is not limited to the heart. It is within all blood vessels! Therefore, risk of stroke as well as peripheral artery disease often accompanies the cardiac patient, along with a multitude of ongoing risk factors. This makes treatment of the patient more difficult, as there are many different interacting problems.

 

Myocardial Infarction

Coronary arteries are quite small, so the accumulation of atherosclerotic plaque that occurs in blood vessels may make their presences known first in these blood vessels. As occlusions grow, opportunities arise to block flow in the blood vessels completely. This may occur because of a thrombus (blood clot) or atherosclerotic plaque that ruptures away from the vessel wall and lodges itself downstream. This complete occlusion results in an acute myocardial infarction. Since flow is blocked downstream from the occlusion, location matters!

Myocardial infarction
Figure 1. Image of a blocked artery. Note the dark tissue representing areas not receiving blood supply. These cells will die if flow cannot be restored, leading to a weakened ventricle and possibly death.

 

If the occlusion is towards the end of the coronary artery, the infarct may only affect a small portion of heart muscle. However, if the occlusion occurs near the origin of the artery, then a massive amount of heart muscle will die, and the person may not survive the infarction. Rapid response of emergency systems, and methods to reopen to blockage (i.e. thrombolytic medications, angioplasty) are essential. The myocardial infarction, or “MI” patient may have additional interventions performed prior to entering cardiac rehab, and conditioning the heart muscle to help it recover from the MI will be an essential component of rehab.

 

Peripheral Artery Disease

Another location for vascular disease to manifest is in the small blood vessels of the periphery, the limbs. Most often this occurs in the lower legs. Oxygen rich blood supply to the limbs is restricted, and as a result the muscles rely on anaerobic metabolism to produce the ATP for work. The result is a large accumulation of lactic acid in the lower limbs, accompanied by pain (known as Claudication). Movement is typically very restricted in these individuals, where they will feel pain within minutes of movement .

Peripheral artery disease
Figure 2. Peripheral artery disease in a lower leg.

 

Recovery only comes by resting to allow clearance of blood from the affected area. Exercise physiologists can assess blood flow in the limbs using a pulse doppler along with a blood pressure cuff and measure the ankle brachial index. Individuals with peripheral artery disease are at risk of losing their limb, due to infection and lack of wound healing. So, exercise will be a very important part of their rehabilitation! Exercise for these individuals will be done in short intervals, with the goal of revascularizing the limbs to provide more blood flow to the tissue.

Ankle-Brachial Index measurement with pulse doppler
Figure 3. Using a pulse doppler probe and blood pressure cuff to measure the Ankle-Brachial Index (ankle systolic/brachial systolic)

 

Heart Failure

Heart failure is the progressive failing of the heart as a pump to eject blood into systemic circulation. Ejection fraction drops over time, resulting in a reduced ability to do physical work, severe deconditioning, fluid retention and edema and ultimately death. There are a number of causes, but hypertension is a major factor in most cases.

Systolic heart failure
Figure 4. The pathways to heart failure. The initial trigger is a load against the ventricle, like high blood pressure or a weak muscle after MI.

 

Patients will display symptoms of dyspnea, have elevated resting heart rates, and are probably taking diuretic medication, among other things. Exercise planning and symptom monitoring of these patients will be unique.

 

Valve Disorders

Since the heart is a series of 4 chambers, and blood flow needs to move in one direction, heart valves are essential to sealing the chambers at one end, while allowing blood to move out of the chamber in the desired direction. Valvular heart disease manifests in one of more of the heart valves. The mitral and aortic valves on the left side of the heart, and the pulmonic and tricuspid valve on the right side of the heart.  Conditions typically relate to the valve not opening properly due to a valve stenosis (i.e. calcification) or perhaps regurgitation of blood backwards through a valve because it is not closing properly (i.e. mitral valve regurgitation or prolapse). The valve disorder can greatly affect heart function, such as ejection fraction and may also precipitate heart arrhythmias. The underlying causes can range from infection to heart disease. Fortunately, today’s medical technology has methods of replacing defective heart valves, so post-surgical patients can enter cardiac rehab to begin to train their heart to regain its conditioning .

Valve disorders
Figure 5. Various forms of mitral valve regurgitation. Damage may be in the leaflet, the chordae tendineae or the surrounding annulus. The result is reduced outflow from the ventricle and a regurgitation of blood backwards into the atria.

 

Heart Dysrhythmias in the Ventricle and the Atria

Heart arrhythmias can occur under a variety of circumstances, and may be congenital in nature, or related to heart disease. In some cases, arrhythmias can be fatal, such as ventricular tachycardia and ventricular fibrillation. To save the individual, shocking the heart using an AED (automated external defibrillator) may be the only solutions. There are some cardiac patients prone to fatal heart arrhythmias or simply need help pacing their heart due to conduction defects in the heart’s electrical system. For this reason, patients may have pacemaker installed in their chest and heart, often along with an internal defibrillator.

Pacemaker
Figure 6. Placement of internal pacemaker-defibrillator. The pacemaker can monitor heart rhythm, assist with heart rhythm, and defibrillate in cases of cardiac arrest.

 

example of Vfib defibrillation back to sinus rhythm
Figure 7. Example of a patient that was in ventricular fibrillation (cardiac arrest). A shock was delivered, and the patient returned to a sinus rhythm.

 

Atrial Fibrillation

Fibrillation can also occur in the atria, often originating around the pulmonary veins in the left atria. Instead of a single sinus beat, where both atria contract to move blood to the ventricle, many cells in the atria are firing randomly, resulting in no atrial contraction.

Top rhythm is normal, bottom rhythm is atrial fibrillation
Figure 8. Atrial Fibrillation. Note the regular rhythm and clear p waves in the top images. Bottom image of afib shows no visible P waves and an irregular rhythm.

 

If the atria are not contracting, blood will pool in some pockets of the atrial (left atrial appendage). Pooling blood forms clots, which can be pushed into the aorta and to the brain causing a stroke. Treatments are to get the patient out of “afib” as soon as possible, try to isolate the initiating tissue and treat patients with medications designed to prevent blood clots.

 

Example of a blood clot from atrial fib migrating to the brain
Figure 9. Example of a blood clot or thrombus migrating from the atria, into the ventricle and then pumped into the systemic system and to the brain, causing a stroke.

 

Exercise physiologists may work with any or all the cardiac conditions identified in the overview. In-depth knowledge of the condition, related ECG information, medications and any symptomology are all important to effectively treat the patient.

 

Selected Sources

Clinical Exercise Physiology 5th ed.   Ehrman, J et al.  Human Kinetics ISBN -10 1718200447 2022.

Cardiac Rehabilitation (Contemporary cardiology) Krause and Keteyian Humana Pub. ISBN-10 1588297705 2007.

 

 

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